Oh absolutely. I use a nifty-keen-awesome program called Calibre for all of my Kindle management. It'll convert pdfs to the azw or mobi formats with pretty good accuracy - sometimes not all the formatting comes across, but I've found if it's a well-made PDF, it generally converts just fine.

Also the excellence of the whole 'lack of back-lighting' issue is not to be overstated. I read a lot on my computer and use to on my phone and never really felt like I was straining to, but the LACK of eye strain on a Kindle is noticeable.